Where vision meets computation.

PershingLab advances eye care through AI, imaging informatics, and data science.

The lab for computational ophthalmology

We develop and apply machine learning, computer vision, natural language processing, and large language models (LLMs) to ophthalmic data from the IRIS® Registry and other sources—electronic health records, imaging, and surgical video—to improve diagnosis, prognosis, and patient outcomes.

Our work is centered on the American Academy of Ophthalmology IRIS® Registry and sits at the intersection of ophthalmology, biomedical informatics, and artificial intelligence. We use IRIS Registry data for real-world evidence, outcomes research, and method development, and we collaborate closely with clinicians and national registry initiatives.

EHR + Imaging + NLP + LLM

Structured and free-text clinical data, OCT, visual fields, and LLM-driven analysis.

Clinical impact takes more than algorithms

We deliver the data infrastructure, methods, and clinical partnerships needed to bring AI from research to patient care.

Research at scale

Multicenter EHR, imaging, and registry data with rigorous phenotyping, outcome definitions, and LLM-supported analytics.

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Data & tools

Claims and registries, de-identified clinical notes, and IRIS® Registry data for research.

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Clinical collaboration

Close partnership with Byers Eye Institute clinicians and national registries including IRIS®.

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Training & dissemination

Fellows, residents, and collaborators trained in ophthalmic informatics and AI methods.

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Engineered for vision science & AI

We develop and apply ML, computer vision, NLP, and large language models (LLMs) to ophthalmic data—from EHR and imaging to surgical video—to improve diagnosis, prognosis, and patient outcomes.

Glaucoma progression & surgery

AI models to predict glaucoma progression and surgical outcomes using multicenter EHR and imaging data.

Computer vision for surgery

Deep learning on cataract and other surgical videos for skill assessment and outcome prediction.

NLP & LLMs for clinical text

Natural language processing and large language models on ophthalmic clinical notes for phenotyping, information extraction, and decision support.

Visual prognosis

Predicting visual prognosis for low-vision patients to support rehabilitation and care planning.

People

Suzann Pershing, MD, MS

Principal Investigator

Chief of Ophthalmology at VA Palo Alto; Vice Chair for Education, Stanford Ophthalmology. Ophthalmic informatics, AI, and predictive modeling in eye care.

Md Enamul Haque, PhD

Sr Data Scientist

Sr Data Scientist at Stanford. Data science and analytics for ophthalmic research, clinical outcomes, and predictive modeling in eye care.

Luay Abdeljaber, PhD

Data Scientist

Data Scientist at Stanford. Data science and informatics for vision and eye care; medical AI, NLP, and active learning in ophthalmology.

Postdocs, students, collaborators

Join us — we're always looking for talented researchers.

Selected publications

Year
Topic
  • 2024

    Evaluating Visual Acuity in the American Academy of Ophthalmology IRIS® Registry

    Ophthalmology Science. Brant A, Kolomeyer N, Goldberg JL, Haller J, Lee CS, Lee AY, Lorch AC, Miller JW, Hyman L, Pershing S.

    PubMed
  • 2024

    Using Natural Language Processing to Identify Different Lens Pathology in Electronic Health Records

    American Journal of Ophthalmology. Stein JD, Zhou Y, Andrews CA, Kim JE, Addis V, Bixler J, Grove N, McMillan B, Munir SZ, Pershing S, Schultz JS, Stagg BC, Wang SY, Woreta F.

    PubMed
  • 2023

    Cataract Surgery in the Medicare Merit-Based Incentive Payment System: Episode-Based Cost Measure Development and Evaluation

    Ophthalmology Science. Pershing S, Sandhu AT, Uwilingiyimana AS, Glasser DB, Morgenstern AS, Do R, Choradia N, Lin E, Leoung J, Shah M, Liu A, Lee J, Fairchild A, Lam J, MaCurdy TE, Nagavarapu S, Bhattacharya J.

    PubMed
  • 2023

    Impact of Type 2 Diabetes Mellitus and Insulin Use on Progression to Glaucoma Surgery in Primary Open Angle Glaucoma

    Eye. Sun MT, Pershing S, Goldberg JL, Wang SY.

    PubMed
  • 2023

    US Population Disparities in Ophthalmic Care: Blindness and Visual Impairment in the IRIS® Registry

    Ophthalmology. Brant A, Kolomeyer N, Goldberg JL, Haller J, Lee CS, Lee AY, Lorch AC, Lum F, Miller JW, Parke DW, Hyman L, Pershing S.

    PubMed
  • 2023

    Thyroid Eye Disease and its Vision Threatening Manifestations in the Academy IRIS® Registry: 2014–2018

    American Journal of Ophthalmology. Ramesh S, Zhang QE, Sharpe J, Penne R, Haller J, Lum F, Lee AY, Lee CS, Pershing S, Miller JW, Lorch A, Hyman L.

    PubMed
  • 2023

    Causes of Childhood Blindness in the United States using the IRIS Registry

    Ophthalmology. Lim HW, Pershing S, Moshfeghi DM, Heo H, Haque ME, Lambert SR, IRIS Registry Analytic Center Consortium.

    PubMed
  • 2023

    Analysis of the Readability and Accountability of Online Patient Education Materials Related to Glaucoma Diagnosis and Treatment

    Clinical Ophthalmology. Cohen SA, Fisher AC, Pershing S.

    PubMed
  • 2023

    Identifying Strategies to Reduce Low-Value Preoperative Testing for Low-Risk Procedures: a Qualitative Study

    Journal of General Internal Medicine. Harris AH, Finlay AK, Hagedorn HJ, Manfredi L, Jones G, Kamal RN, Sears ED, Hawn M, Eisenberg D, Pershing S, Mudumbai S.

    PubMed
  • 2022

    The American Academy of Ophthalmology IRIS Registry: Current and Future State of Big Data Analytics

    Current Opinion in Ophthalmology. Pershing S, Lum F.

    PubMed
  • 2022

    Effectiveness of Microinvasive Glaucoma Surgery in the United States: IRIS Registry Analysis 2013–2019

    Ophthalmology. Yang S, Ciociola EC, Mitchell W, Hall N, Lorch AC, Miller JW, Friedman DS, Boland MV, Elze T, Zebardast N, IRIS Registry Analytic Center Consortium.

    PubMed
  • 2022

    Outcomes of Over 40,000 Eyes Treated for Diabetic Macula Edema in Routine Clinical Practice: A Systematic Review and Meta-analysis

    Advances in Therapy. Mehta H, Nguyen V, Barthelmes D, Pershing S, Chi GC, Dopart P, Gillies MC.

    PubMed
  • 2022

    Adjustable suture technique is associated with fewer strabismus reoperations in the IRIS Registry

    Ophthalmology. Oke I, Hall N, Elze T, Miller JW, Lorch AC, Hunter DG, IRIS Data Analytics Committee members, Pershing S, Hyman L, Haller JA, Lee AY, Lee CS, Lum F, Miller JW, Lorch A.

    PubMed
  • 2022

    Relative Importance of Applicant Characteristics in Ophthalmology Residency Interview Selection: A Survey of Program Directors

    Journal of Academic Ophthalmology. Cohen SA, Pershing S.

    PubMed
  • 2022

    Readability and accountability of online patient education materials for common retinal diseases

    Ophthalmology Retina. Cohen SA, Pershing S.

    PubMed
  • 2022

    Predicting Acute Endophthalmitis for Patients with Cataract Surgery Using Hierarchical and Probabilistic Representation of Clinical Codes

    International Journal of Semantic Computing. Haque M, Pershing S.

  • 2021

    Implicit Bias and the Association of Redaction of Identifiers With Residency Application Screening Scores

    JAMA Ophthalmology. Pershing S, Stell L, Fisher AC, Goldberg JL.

    PubMed
  • 2021

    Endophthalmitis rate in immediately sequential vs delayed sequential bilateral cataract surgery within the IRIS Registry

    Ophthalmology. Lacy M, Kung TH, Owen JP, Yanagihara RT, Blazes M, Pershing S, Hyman LG, Van Gelder RN, Lee AY, Lee CS, IRIS Registry Analytic Center Consortium.

    PubMed
  • 2021

    Bidirectional Association between Visual Impairment and Dementia Among US Older Adults Over Time

    Ophthalmology. Chen SP, Azad AD, Pershing S.

    PubMed
  • 2021

    Variability and Costs of Low-Value Preoperative Testing for Cataract Surgery Within the Veterans Health Administration

    JAMA Network Open. Mudumbai SC, Pershing S, Bowe T, Kamal RN, Sears ED, Hawn MT, Eisenberg D, Finlay AK, Hagedorn H, Harris AH.

    PubMed
  • 2021

    Need for Retinal Detachment Reoperation based on Primary Repair Method among Commercially-insured Patients, 2003–2016

    American Journal of Ophthalmology. Reeves MR, Afshar AR, Pershing S.

    PubMed
  • 2021

    Age, Gender, and Laterality of Retinal Vascular Occlusion: A Retrospective Study from the IRIS Registry

    Ophthalmology Retina. Li Y, Hall NE, Pershing S, Hyman L, Haller JA, Lee AY, Lee CS, Chiang M, Lum F, Miller JW, Lorch A, Elze T.

    PubMed
  • 2021

    The Impact of COVID-19 on Missed Ophthalmology Clinic Visits

    Clinical Ophthalmology. Brant AR, Pershing S, Hess O, Rooney D, Goldberg J, Tabin G, Wang SY.

    PubMed
  • 2020

    Receipt of Eye Care Services among Medicare Beneficiaries with and without Dementia

    Ophthalmology. Pershing S, Goldstein MK, Henderson VW, Bundorf MK, Lu Y, Rahman M, Stein JD.

    PubMed
  • 2020

    Comparing cataract surgery complication rates in veterans receiving VA and community care

    Health Services Research. Rosen AK, Vanneman ME, O'Brien WJ, Pershing S, Wagner TH, Beilstein-Wedel E, Lo J, Chen Q, Cockerham GC, Shwartz M.

    PubMed
  • 2020

    Big data requirements for artificial intelligence

    Current Opinion in Ophthalmology. Wang SY, Pershing S, Lee AY, AAO Taskforce on AI and AAO Medical Information Technology Committee.

    PubMed
  • 2020

    Intraocular Pressure Changes after Cataract Surgery in Patients with and without Glaucoma: An Informatics-Based Approach

    Ophthalmology Glaucoma. Wang SY, Azad AD, Lin SC, Hernandez-Boussard T, Pershing S.

    PubMed
  • 2020

    Cataract Surgery Complexity and Surgical Complication Rates among Medicare Beneficiaries with and without Dementia

    American Journal of Ophthalmology.

    PubMed
View all publications on Stanford Profiles →

Data & tools

Clinical data & registries

Structured EHR, ophthalmic imaging (OCT, visual fields), IRIS® Registry data, and de-identified clinical notes for research.

Claims & registries

Analysis of glaucoma risk factors and surgical outcomes using insurance claims and national registries.

Get in touch

Byers Eye Institute at Stanford
Stanford University School of Medicine

For collaborations, data access, or joining the lab, please reach out via Stanford Medicine channels.

Department of Ophthalmology

Work with us